Autosomal Dominant Polycystic Kidney Disease Market Report gives readers a thorough assessment of key market drivers, restraints, prospects, opportunities, restraints, current trends, and technological and industrial breakthroughs that will influence market growth. The detailed market research, industry sector growth and development, and new product introductions covered in this report on the Autosomal Dominant Polycystic Kidney Disease Market are of great assistance to the important new commercial players joining the market.
This Autosomal Dominant Polycystic Kidney Disease Market report research conducts a careful market evaluation and provides a professional analysis of the industry taking into account market development, present market circumstances, and forecasts for the future. The market driving factors, market overview, industry volume, and market share are also highlighted in this Autosomal Dominant Polycystic Kidney Disease Market report analysis.
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Autosomal Dominant Polycystic Kidney Disease: An Overview
Autosomal Dominant Polycystic Kidney Disease (ADPKD) is a genetic disorder which causes pathological cystic changes to the kidney and is characterized by numerous renal and systemic manifestations. Renal manifestations are produced by the progressive and continuous enlargement and proliferation of fluid-filled cysts, leading to enlargement of the kidney up to five times the normal volume in the years prior to the development of kidney failure. ADPKD may lead to development of end-stage renal disease (ESRD) and is the fourth most common renal disease requiring renal replacement therapy (RRT). The most common extra-renal manifestation is polycystic liver disease (PLD), which is more common in women than in men.
Key highlights of the Autosomal Dominant Polycystic Kidney Disease Market Report
Autosomal Dominant Polycystic Kidney Disease Epidemiology Insights
A Large-scale cohort study of 541 Chinese ADPKD patients with a mean follow-up time of 14.3 months and mean age was 39.5 years demonstrated that three fourths of the patients had a family history of ADPKD. Nearly 75% of the patients had polycystic liver disease; 37% of the patients had chronic pain, and 23% had an episode of gross hematuria (Cheng Xue et al., 2016)
Autosomal Dominant Polycystic Kidney Disease Epidemiology Segmentation in the 7MM
Autosomal Dominant Polycystic Kidney Disease Treatment Market
Currently approved treatment options are mainly focused to slow the progression of ADPKD with reducing the size of the cyst. The therapeutic market size is accounted by therapies directed toward the management of kidney and non-kidney symptoms associated with the disease and it is based on prophylactic and supportive measures. Specifically, the treatment aims for blood pressure (BP) control and maximal inhibition of the renin-angiotensin-aldosterone system (RAAS) on progressive renal disease and cardiovascular manifestations in ADPKD. The kidney transplantation, frequent dialysis procedures along with nutritional supplements are also driving the market. The therapeutic market is driven by the increase in prevalent cases and is mainly driven by the patient pools of older ages.
Autosomal Dominant Polycystic Kidney Disease Market Insights
There is no cure for ADPKD and it not possible to stop cysts forming in the kidneys, however, a lot of research has been done in this space to find the ways to manage the disease. Majority of patients with ADPKD will eventually develop ESRD and require RRT. The progressiveness of this disease and its complications cause debilitating effects on health of patients and impose a significant burden, both economically and on the quality of life.
Autosomal Dominant Polycystic Kidney Disease Market Forecast
The research has helped now to understand the genetic and molecular basis of disease and the complex pathways in regulating the formation and development of cysts are being elucidated. New targeted therapies are available and can be tested in ADPKD, with the hope to find a cure or impact this disorder with novel therapeutic targets. Vigorous attempts have been done to develop medications to slow the
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